Relation of Testosterone Normalization to Mortality and Myocardial Infarction in Men With Previous Myocardial Infarction 2019

This is a spectacular 2019 article that shows the safety and, in fact, the cardiovascular health improvement  that can be seen with Testosterone Replacement Therapy (TRT).  These authors studied 1,470 men with a history pre-existing high cardiac risk, know history of prior heart attack and known low testosterone levels.  They then studied recurrent heart disease…

Testosterone and the Heart 2019

Men with Testosterone deficiency tend to have a portfolio of cardiac risk factors that include Type 2 Diabetes and Metabolic Syndrome.  Testosterone deficiency increases the risk of Cardiovascular disease and the risk of developing Type 2 diabetes and metabolic syndrome.  Many of the key symptoms of low Testosterone are sexual in nature, including erectile dysfunction,…

A New Independent Risk Factor for Heart Disease 2012

Previously identified risk factor for coronary artery and heart disease were age, low high-density lipoprotein (good cholesterol), and free testosterone.  However, free testosterone may be the strongest predictor of coronary artery disease than other factors such as blood pressure, cholesterol, diabetes, smoking and body mass index (obesity). An overwhelming volume of data shows that higher…

Hypogonadism as a risk factor for cardiovascular mortality in men: a meta-analytic study – 2011 – European Society of Endocrinology

A previous major summary study evaluating the effect of Testosterone Therapy on Cardiovascular Events, showed Testosterone Therapy safety, because it was not associated with an increased risk of Cardiovascular Disease.  Similar results were also reported in another review that analyzed 51 placebo-controlled studies with follow-up ranging from 3 months up to 3 years.  While higher…

Effects of transdermal estrogen on levels of lipids, lipase activity, and inflammatory markers in men with prostate cancer – 2006 – Journal of Lipid Research

In this study, Estradiol was shown to: 1. Decrease (bad cholesterol markers) Total cholesterol, LDL cholesterol, and apolipoprotein B levels and increase (good cholesterol markers) HDL2 cholesterol.  Estradiol improves lipid profile, Cardiovascular Disease and mortality rates. READ FULL ARTICLE

Effects of Testosterone Administration on Fat Distribution, Insulin Sensitivity, and Atherosclerosis Progression – 2003 – Clinical Infectious Disease

In epidemiological studies, serum total and free testosterone concentrations have been inversely correlated with intra-abdominal fat mass, risk of coronary artery disease, and type 2 diabetes mellitus. Testosterone administration to middle-aged men is associated with decreased visceral fat and glucose concentrations and increased insulin sensitivity. Testosterone infusion increases coronary blood flow. Similarly, testosterone replacement retards…